The importance of nicotine in cigarettes has to do with its effects on the brain. This is not a new revelation. Centuries ago it was recognized that snuff products "Mind altering" effects, it was a "brain food." We now know that many of these effects are not unique to nicotine, but share with most drugs of abuse. To understand why people smoke cigarettes when I know it is harmful to your health, it will be useful to know that nicotine in the brain.

How does nicotine in the brain

To affect the brain, a drug that have physical properties that allow it to cross the blood-brain barrier (the barrier that protects the brain from foreign substances). The nicotine molecule is ideal physical characteristics that allow you to enter in the brain with ease. When nicotine is inhaled into the lungs, blood, blood that collects and brings it to the brain in 10 seconds.

Once in the brain, the molecules key role of nicotine as the opening of the locks. The locks are called "receptors" and are found in nerve cells in the brain and connect to muscle tissue and various organs of the body. Drugs that act as keys are called "transmitters", helping to transmit information from one part of the body to another.

The receptors on the receiving end (dendrites) of nerve cells transmit information by electrical impulses along the axon. In the end axon terminal of a small amount of the issuer's own body chemicals (eg adrenaline) is released. The transmitter passes through the gap (synapse) where it has its effect on the body end, the goal may be another nerve cell, which failed, a body like the heart that is racing, or muscle that is stimulated.

Nicotine has been complicated by the actions activated receptors that are located throughout the body. In fact, much of the nervous system mapping was out by placing nicotine in different places and the effects of assignment. This is very similar to the allocation of the undercurrents in a lake and river system by placing dyes in water and the layout of your course.

The areas that were activated by nicotine are called nicotinic receptors. A few of These receptors are located in the adrenal gland. The action of these results in the release of epinephrine and norepinephrine in the body. These chemical products increased heart rate, blood pressure, increase arousal, and cause feelings of excitement. Cocaine also causes increased activity of adrenaline and has effects on the brain similar to nicotine.

A drug that activates a receptor called an "agonist." Other substances share certain essential characteristics physical properties of the agonists can replace agonists – like a master key may be replaced by a special key. For example, codeine, morphine and heroin can replace all each other. You only need to adjust the dose to achieve the same effect.

Nicotine acts by substitution of Chemical body (acetylcholine) in the nicotinic receptors. mass transfer line contained in a computer desk help you stop smoking, which is part of nicotine replacement. The form of nicotine gum newly marketed (Nicolette) substitutes nicely for the nicotine in smoke of snuff. Amphetamine appears to replace some of the effects of nicotine. Both drugs increase the activity of adrenaline and noradrenaline.

A drug that blocks the effect of an agonist is called an antagonist. Some drugs act as antagonists in stimulating other systems (functional antagonists). For example, giving coffee to a person who is intoxicated by alcohol produces the famous "waking up drunk" phenomenon. Other drugs act as antagonists by occupying receptor without all the effects of their own, which prevents the working agonist (competitive antagonists). It's like filling a keyhole with wax, thus preventing the entry key. Nicotine is called antagonist mecamylamine. Mecamylamine and similar drugs (ganglion blockers) are now used to treat patients with high blood pressure. They are being tested as a possible help to quit smoking, because they block the pleasurable effects of nicotine.

I am happy to say that after being virtually chain smokers my husband and myself both gave up smoking 12 years or more ago!

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